DCTN2 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12893c
Background:
This gene encodes a 50-kD subunit of dynactin, amacromolecular complex consisting of 10-11 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation, chromosomemovement, nuclear positioning, and axonogenesis. This subunit ispresent in 4-5 copies per dynactin molecule. It contains threeshort alpha-helical coiled-coil domains that may mediateassociation with self or other dynactin subunits. It may interactdirectly with the largest subunit (p150) of dynactin and may affixp150 in place.
Other Names:
Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Gene Name: DCTN2 (HGNC:2712)
Gene ID: 10540
Primary Accession: Q13561
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a 50-kD subunit of dynactin, amacromolecular complex consisting of 10-11 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation, chromosomemovement, nuclear positioning, and axonogenesis. This subunit ispresent in 4-5 copies per dynactin molecule. It contains threeshort alpha-helical coiled-coil domains that may mediateassociation with self or other dynactin subunits. It may interactdirectly with the largest subunit (p150) of dynactin and may affixp150 in place.
Other Names:
Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Gene Name: DCTN2 (HGNC:2712)
Gene ID: 10540
Primary Accession: Q13561
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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