DCTN2 antibody (clone 2G7), anti-human
€435.00
In stock
SKU
AC-AT1722a
Catalog Number: AC-AT1722a
Size: 100 µg
Isotype: mouse IgG1 lambda
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 lambda
Applications: WB, IF, E
Request Information AC-AT1722a">Request Information
Background:
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Other Names:
Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Antigen Type:
Recombinant Protein
Gene Name: DCTN2 (HGNC:2712)
Gene ID: 10540
NCBI Accession: NP_001248341.1;NP_001248342.1;NP_006391.1
Primary Accession: Q13561
Other Accession: BC000718
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Other Names:
Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Antigen Type:
Recombinant Protein
Gene Name: DCTN2 (HGNC:2712)
Gene ID: 10540
NCBI Accession: NP_001248341.1;NP_001248342.1;NP_006391.1
Primary Accession: Q13561
Other Accession: BC000718
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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