DCTN2 polyclonal (Center), anti-human
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In stock
SKU
AC-AP12893c
Catalog Number: AC-AP12893c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19599
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19599
Applications: WB, IHC-P
Datasheet
Request Information
Background:
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Other Names:
Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Target/Specificity:
This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2.
Antigen Region:
192-219
Antigen Type: Synthetic Peptide
Gene Name: DCTN2 (HGNC:2712)
Gene ID: 10540
Primary Accession: Q13561
NCBI Accession: NP_001248341.1;NP_001248342.1;NP_006391.1
Other Accession: Q6AYH5; Q99KJ8; Q3ZCF0; NP_006391.1; A0A5G2QD80
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Other Names:
Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Target/Specificity:
This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2.
Antigen Region:
192-219
Antigen Type: Synthetic Peptide
Gene Name: DCTN2 (HGNC:2712)
Gene ID: 10540
Primary Accession: Q13561
NCBI Accession: NP_001248341.1;NP_001248342.1;NP_006391.1
Other Accession: Q6AYH5; Q99KJ8; Q3ZCF0; NP_006391.1; A0A5G2QD80
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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