DCTN3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP17778c
Background:
This gene encodes the smallest subunit of dynactin, amacromolecular complex consisting of 10 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation,cytokinesis, chromosome movement, nuclear positioning, andaxonogenesis. This subunit, like most other dynactin subunits,exists only as a part of the dynactin complex. It is primarily analpha-helical protein with very little coiled coil, and bindsdirectly to the largest subunit (p150) of dynactin. Alternativesplicing of this gene generates 2 transcript variants. [provided byRefSeq].
Other Names:
Dynactin subunit 3, Dynactin complex subunit 22 kDa subunit, p22, DCTN3 {ECO:0000312|EMBL:CAG466871}, DCTN22
Gene Name: DCTN3 {ECO:0000312|EMBL:CAG46687.1}
Gene ID: 11258
Primary Accession: O75935
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the smallest subunit of dynactin, amacromolecular complex consisting of 10 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation,cytokinesis, chromosome movement, nuclear positioning, andaxonogenesis. This subunit, like most other dynactin subunits,exists only as a part of the dynactin complex. It is primarily analpha-helical protein with very little coiled coil, and bindsdirectly to the largest subunit (p150) of dynactin. Alternativesplicing of this gene generates 2 transcript variants. [provided byRefSeq].
Other Names:
Dynactin subunit 3, Dynactin complex subunit 22 kDa subunit, p22, DCTN3 {ECO:0000312|EMBL:CAG466871}, DCTN22
Gene Name: DCTN3 {ECO:0000312|EMBL:CAG46687.1}
Gene ID: 11258
Primary Accession: O75935
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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