DDAH2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8231
Background:
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation . DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) . DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Alternative Name:
N(G), N(G)-dimethylarginine dimethylaminohydrolase 2, DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase protein, DDAH2, DDAH, G6A, NG30
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:10 - 1:100
Specificity: DDAH2 polyclonal antibody detects endogenous levels of DDAH2 protein.
Immunogen:
Recombinant full length Human DDAH2.
MW: ~ 30 kDa
Swis Prot.: O95865
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation . DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) . DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Alternative Name:
N(G), N(G)-dimethylarginine dimethylaminohydrolase 2, DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase protein, DDAH2, DDAH, G6A, NG30
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:10 - 1:100
Specificity: DDAH2 polyclonal antibody detects endogenous levels of DDAH2 protein.
Immunogen:
Recombinant full length Human DDAH2.
MW: ~ 30 kDa
Swis Prot.: O95865
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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