DDC Polyclonal Antibody

Background:
The encoded protein catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Research Area: Neuroscience,Cancer,Metabolism

Synonyms:
AADC, Aromatic L Amino Acid Decarboxylase, Aromatic-L-amino-acid decarboxylase, DDC, DDC_HUMAN, DOPA decarboxylase (aromatic L-amino acid decarboxylase), DOPA decarboxylase

Immunogen: Synthetic peptide of human DDC

Swissprot: P20711
Gene Accession: NP000781

Calculated MW: 54 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.