DDX1 Polyclonal Antibody

Background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
ATP dependent helicase DDX1, ATP-dependent RNA helicase DDX1, DBP RB , DBP-RB, DDX1, DDX1, DEAD (Asp Glu Ala Asp) box polypeptide 1, DEAD box 1, DEAD box polypeptide 1, DEAD box protein 1, DEAD box protein retinoblastoma, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 1

Immunogen: Fusion protein of human DDX1

Swissprot: Q92499
Gene Accession: BC012132

Calculated MW: 82 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.