DDX1 Polyclonal Antibody

Background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DDX1, DBP-RB, UKVH5d

Immunogen: Recombinant fusion protein of human DDX1 (NP_004930.1).

Swissprot: Q92499
Gene ID: 1653

Calculated MW: 68 kDa/69 kDa/82 kDa
Observed MW: 100 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.