DDX11 Polyclonal Antibody

Background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
CHL1, CHL1 related helicase gene 1, CHL1-like helicase homolog, CHL1-related protein 1, CHLR1, Ddx11, DDX11, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 11, DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), DEAD/H box, DEAD/H box protein 11, hCHLR1, Keratinocyte growth factor regulated gene 2 protein, Keratinocyte growth factor-regulated gene 2 protein, KRG 2, KRG-2, KRG2, MGC133249, MGC9335, OTTHUMP00000238778, OTTHUMP00000238780, OTTHUMP00000238784, OTTHUMP00000238785, Probable ATP dependent RNA helicase DDX11, Probable ATP-dependent RNA helicase DDX11, WABS

Immunogen: Recombinant protein of human DDX11

Swissprot: Q96FC9
Gene Accession: NP_689651

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-68468/sc-68855