DDX11 Polyclonal Antibody

Background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
DDX11, CHL1, CHLR1, KRG2, WABS

Immunogen: Recombinant fusion protein of human DDX11 (NP_689651.1).

Swissprot: Q96FC9
Gene ID: 1663

Calculated MW: 32 kDa/96 kDa/98 kDa/101 kDa/108 kDa
Observed MW: 108 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.