DDX3 (clone 6G8-F4-E3), anti-human, mouse, rat, monkey

Background:
DEAD box proteins,characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD),are putative RNA helicases.They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation,nuclear and mitochondrial splicing,and ribosome and spliceosome assembly.Based on their distribution patterns,some members of this family are believed to be involved in embryogenesis,spermatogenesis,and cellular growth and division.This gene encodes a DEAD box protein,which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location.This gene has a homolog located in the nonrecombining region of the Y chromosome.The protein sequence is 91% identical between this gene and the Y-linked homolog.Alternative splicing results in multiple transcript variants.[provided by RefSeq,Jul 2010]

Synonyms: CAP-Rf, DBX, DDX14, DDX3, HLP2, MRX102

Cellular Location: Cytoplasm Mitochondrion outer membrane Nucleus speckle

Immunogen:
Purified recombinant human DDX3 protein fragments expressed in E.coli.

Gene Symbol: DDX3

Gene ID: 1654

Swiss prot: O00571

Calculated MW: 75kDa

Recommended dilution:
WB 1:1000, ICC 1:200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.