DDX3 polyclonal (C-term), anti-human

DDX3 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP1483b
Catalog Number: AC-AP1483b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13438
Applications: IHC-P, WB
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Background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX3 is a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. The DDX3 gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.

Other Names:
ATP-dependent RNA helicase DDX3X, DEAD box protein 3, X-chromosomal, DEAD box, X isoform, Helicase-like protein 2, HLP2, DDX3X, DBX, DDX3

Target/Specificity:
This DDX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-485 amino acids from the C-terminal region of human DDX3.

Antigen Region:
456-485

Antigen Type: Synthetic Peptide

Gene Name: DDX3X
Gene ID: 1654
Primary Accession: O00571
NCBI Accession: NP_001180346.1;NP_001347.3
Other Accession: P24346; O15523; Q62167; P16381
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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