DDX39A Polyclonal Antibody

Background:
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
ATP dependent RNA helicase DDX39, ATP-dependent RNA helicase DDX39A, BAT1, BAT1L, DDX39, DDXL, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 isoform 2, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A, DEAD box protein 39, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39, Eukaryotic initiation factor 4a, Nuclear RNA helicase URH49, Nuclear RNA helicase, DECD variant of DEAD box family, UAP56 related helicase, UAP56 related helicase, 49 kDa, URH49, wu:fc87b12, zgc:55881

Immunogen: Fusion protein of human DDX39A

Swissprot: O00148
Gene Accession: BC001009

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.