DDX5 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
DDX5(DEAD/H BOX 5), also known as HLR1 or G17P1, is an enzyme that in humans is encoded by the DDX5 gene. The p68 protein is a proliferation-associated nuclear antigen first identified through its highly specific cross-reaction with the simian virus 40 tumor antigen(Iggo et al., 1989). Subsequently, homology to eukaryotic translation initiation factor was found, and amino acid sequence blocks characteristic of a large superfamily of proteins with putative helicase activity were demonstrated. Brody et al.(1995) confirmed that this gene is located on chromosome 17 in the region of the BRCA1 gene at 17q21. By immunoprecipitation analysis, Caretti et al.(2006) found that p68, p72(DDX17), and the noncoding RNA SRA(SRA1) associated with MYOD(MYOD1) in MYOD-transfected HeLa cells.

Description:
Rabbit IgG polyclonal antibody for Probable ATP-dependent RNA helicase DDX5 (DDX5) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
ATP dependent RNA helicase DDX5 antibody, DDX 5 antibody, Ddx5 antibody, DDX5_HUMAN antibody, DEAD(Asp Glu Ala Asp) box helicase 5 antibody, DEAD(Asp Glu Ala Asp) box polypeptide 5 antibody, DEAD box 5 antibody, DEAD box protein 5 antibody, DEAD/H(Asp Glu Ala Asp/His) box polypeptide 5(RNA helicase, 68kD) antibody, DEAD/H(Asp Glu Ala Asp/His) box polypeptide 5 antibody, DEAD/H(Asp-Glu-Ala-Asp/His) box polypeptide 5(RNA helicase 68kDa) antibody, DEAD/H box-5(RNA helicase 68kD) antibody, DKFZp686J01190 antibody, G17P1 antibody, HELR antibody, HLR 1 antibody, HLR1 antibody, HUMP68 antibody, P68 antibody, p68 RNA helicase antibody, Probable ATP dependent RNA helicase DDX5 antibody, Probable ATP-dependent RNA helicase DDX5 antibody, RNA helicase 68kD antibody, RNA helicase p68 antibody, RNA-dependent ATPase antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human DDX5(566-580aa TYQNGYDSTQQYGSN), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.