DDX5 polyclonal, anti-human, mouse, rat

Background:
p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase.

Alternative Name:
G17P1, HELR, HLR1, ATP dependent RNA helicase DDX5, DDX 5, Ddx5, DDX5, DEAD (Asp Glu Ala Asp) box helicase 5, DEAD (Asp Glu Ala Asp) box polypeptide 5, DEAD box 5, DEAD box protein 5, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase, 68kD), G17P1, HELR, HLR1, HUMP68, P68, p68 RNA helicase, Probable ATP dependent RNA helicase DDX5, Probable ATP-dependent RNA helicase DDX5, RNA helicase p68,

Application Dilution:
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: DDX5 polyclonal antibody detects endogenous levels of DDX5 protein.

Immunogen:
recombinant protein

MW: 69/60 kDa

Swiss-Prot: P17844(Human) Q61656(Mouse)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.