DDX58 Polyclonal Antibody

Background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology

Synonyms:
Ddx58, DDX58, DEAD (Asp Glu Ala Asp) box polypeptide 58, DEAD (Asp Glu Ala Asp/His) box polypeptide, DEAD box protein 58, DEAD/H (Asp Glu Ala Asp/His) box polypeptide RIG1, DKFZp434J1111, DKFZp686N19181, FLJ13599, Probable ATP dependent RNA helicase DDX58, Probable ATP-dependent RNA helicase DDX58, Retinoic acid inducible gene 1 protein, Retinoic acid-inducible gene 1 protein, Retinoic acid-inducible gene I protein, RIG I, Rig-1, RIG-I, RIG1, rigi, RLR 1, RNA helicase, RNA helicase RIG I, SGMRT2

Immunogen: Synthetic peptide of human DDX58

Swissprot: O95786
Gene Accession: NP055129

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:2000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.