DDX59 Polyclonal Antibody

Background:
DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX59 (DEAD box protein 59), also known as ZNHIT5 (zinc finger HIT domaincontaining protein 5), is a 619 amino acid member of the DEAD box helicase protein family. Like many DEAD box helicase family members, DDX59 contains a Q motif, which controls ATP binding and hydrolysis. Expressed as two isoforms produced by alternative splicing, DDX59 contains one helicase C-terminal domain and one HIT-type zinc finger.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
DDX 59, DDX59, DDX59, DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 , DEAD box protein 59, DKFZP564B1023, OTTHUMP00000033840, OTTHUMP00000033841, Probable ATP-dependent RNA helicase DDX59, RP11-92G12.2, Zinc finger HIT domain containing protein 5 , Zinc finger HIT domain-containing protein 5, ZNHIT5

Immunogen: Fusion protein of human DDX59

Swissprot: Q5T1V6
Gene Accession: BC041801

Calculated MW: 69 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.02 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.