Decorin polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Decorin is a protein that in humans is encoded by the DCN gene. This gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate(CS) or dermatan sulfate(DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines.

Description:
Rabbit IgG polyclonal antibody for Decorin (DCN) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
Bone proteoglycan II antibody, CSCD antibody, DCN antibody, DCN protein antibody, Decorin antibody, Decorin proteoglycan antibody, Dermatan sulphate proteoglycans II antibody, DKFZp686J19238 antibody, DSPG 2 antibody, DSPG2 antibody, PG 40 antibody, PG II antibody, PG S2 antibody, PG-S2 antibody, PG40 antibody, PGII antibody, PGS 2 antibody, PGS2 antibody, PGS2_HUMAN antibody, Proteoglycan core protein antibody, SLRR1B antibody, Small leucine rich protein 1B antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Decorin recombinant protein (Position: D31-K359). Human Decorin shares 80% and 77% amino acid (aa) sequences identity with mouse and rat Decorin, respectively.E.coli-derived human Decorin recombinant protein (Position: D31-K359). Human Decorin shares 80% and 77% amino acid (aa) sequences identity with mouse and rat Decorin, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.