DEDAF polyclonal, anti-human, mouse, rat antibody

Background:
Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and a µgments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.

Other Names:
DEDAF , YEAF1 , AAP1 , APAP-1, RYBP, RING1 and YY1-binding protein, Death effector domain-associated factor, DED-associated factor, YY1 and E4TF1-associated factor 1, Apoptin-associating protein 1, APAP-1

Primary Accession: Q8N488

Gene Name: RYBP

Gene ID: 23429

Concentration (mg/ml): 0.5 mg/ml