DEFB104A Polyclonal Antibody

Background:
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.

Research Area: Immunology, Microbiology

Synonyms:
BD 4, BD-4, BD4, beta 104, Beta defensin 4, Beta-defensin 104, Beta-defensin 4, D104A, DEFB-4, DEFB104B, Defensin, Defensin beta 104, Defensin beta 4 precursor, hBD 4, hBD-4, hBD4

Immunogen: Synthetic peptide of human DEFB104A

Swissprot: Q8WTQ1
Gene Accession: NP525128

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.