DEFB4 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7188
Background:
β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Unlike the other previously described human β-defensins, human β-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse β-defensin 4. Rat β-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regulated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regulation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human β-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed.
Alternative Name:
Beta-defensin 4A, Beta-defensin 2, BD-2, hBD-2, Defensin beta 2, Skin-antimicrobial peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B, β-defensin 4A, Defensin-β2, Defensin β2
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: DEFB4 polyclonal antibody detects endogenous levels of DEFB4 protein.
Immunogen:
Recombinant full length Human DEFB4.
MW: ~ 8 kDa
Swis Prot.: O15263
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Unlike the other previously described human β-defensins, human β-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse β-defensin 4. Rat β-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regulated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regulation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human β-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed.
Alternative Name:
Beta-defensin 4A, Beta-defensin 2, BD-2, hBD-2, Defensin beta 2, Skin-antimicrobial peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B, β-defensin 4A, Defensin-β2, Defensin β2
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: DEFB4 polyclonal antibody detects endogenous levels of DEFB4 protein.
Immunogen:
Recombinant full length Human DEFB4.
MW: ~ 8 kDa
Swis Prot.: O15263
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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