DENND6A Polyclonal Antibody

Background:
Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes.

Research Area: Cell Biology

Synonyms:
F116A, Fam116a, Family with sequence similarity 116 member A, family with sequence similarity 116, member A , FLJ34969, hypothetical protein LOC201627, Protein FAM116A

Immunogen: Fusion protein of human DENND6A

Swissprot: Q8IWF6
Gene Accession: BC040291

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: IHC 1:100-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.