DES Polyclonal Antibody

Background:
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Research Area: Cancer, Cardiovascular, Signal Transduction, Stem Cells

Synonyms:
DES, CSM1, CSM2, LGMD2R, desmin, Desmin

Immunogen: Recombinant fusion protein of human DES (NP_001918.3).

Swissprot: P17661
Gene ID: 1674

Calculated MW: 53 kDa
Observed MW: 54 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.