Desmin (clone 10H7D2), anti-human

Background:
Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Research Area: Others

Synonyms: Desmin

Immunogen: Purified recombinant fragment of Desmin expressed in E. Coli.

Formulation: Purified antibody in PBS containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage