Desmin Polyclonal Antibody

Background:
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Research Area: Cancer, Cardiovascular, Signal Transduction, Stem Cells

Synonyms:
CMD1I, CSM1, CSM2, DES, DESM, Desmin, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865

Immunogen: Synthesized peptide derived from the C-terminal region of human Desmin

Swissprot: P17661

Calculated MW: 54 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.