Desmoglein 2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

Description:
Rabbit IgG polyclonal antibody for Desmoglein-2 (DSG2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
ARVC 10 antibody, ARVC10 antibody, ARVD 10 antibody, ARVD10 antibody, Cadherin family member 5 antibody, CDHF 5 antibody, CDHF5 antibody, CMD1BB antibody, Desmoglein 2 antibody, Desmoglein-2 antibody, Desmoglein2 antibody, DSG 2 antibody, DSG2 antibody, DSG2_HUMAN antibody, HDGC antibody, HDGC included antibody, MGC117034 antibody, MGC117036 antibody, MGC117037 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 2(1104-1118aa STRVTKHSTVQHSYS), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 2(1104-1118aa STRVTKHSTVQHSYS), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.