DFF40 polyclonal, anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10037-100
Catalog Number: AC-ABV10037-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40’s activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary.
Other Names:
DFFB, CAD, DFF-40 , CPAN , DFF2
Primary Accession: O54788
Other Accession: AAH53052
Gene Name: Dffb
Concentration (mg/ml): 0.2 mg/ml
DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40’s activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary.
Other Names:
DFFB, CAD, DFF-40 , CPAN , DFF2
Primary Accession: O54788
Other Accession: AAH53052
Gene Name: Dffb
Concentration (mg/ml): 0.2 mg/ml
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