DFF45 (Cleaved-Ser118) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
Inhibitor of the caspase-activated DNase (DFF40).|PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.|PTM:Phosphorylated upon DNA damage| probably by ATM or ATR.|Contains 1 CIDE-N domain.|subunit:Heterodimer of DFFA and DFFB.|

Research Area: Cancer, Cell biology, Epigenetics and nuclear signaling, Metabolism

Synonyms: DFF45 , Cleaved-Ser118, DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year