DFF45 polyclonal, anti-mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10036-100
Catalog Number: AC-ABV10036-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as many other types of diseases. Recently, a human DNA fragmentation factor (DFF45) was identified. DFF is composed of two subunts: DFF40 and DFF45. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40’s activation as a nuclease. Activation of DFF40 can lead to DNA fragmentation, a hallmark of apoptosis.
Other Names:
DFFA, DFF-45, ICAD, DFF1
Primary Accession: O54786
Other Accession: AAH58213
Gene Name: Dffa
Gene ID: 13347
Concentration (mg/ml): 0.2 mg/ml
Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as many other types of diseases. Recently, a human DNA fragmentation factor (DFF45) was identified. DFF is composed of two subunts: DFF40 and DFF45. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40’s activation as a nuclease. Activation of DFF40 can lead to DNA fragmentation, a hallmark of apoptosis.
Other Names:
DFFA, DFF-45, ICAD, DFF1
Primary Accession: O54786
Other Accession: AAH58213
Gene Name: Dffa
Gene ID: 13347
Concentration (mg/ml): 0.2 mg/ml
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