DGCR8 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Synonyms: DGCR8, DGCRK6, Gy1, C22orf12, D16Wis2, pasha

Gene Name: DGCR8

Gene ID: 54487

SwissProt ID: Q8WYQ5

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.