DGKa (clone M6), anti-human
€564.00
In stock
SKU
ARP-21-5065
Catalog Number: 21-5065
Size: 100 µg
Isotype: Mouse
Size: 100 µg
Isotype: Mouse
Background:
Diacylglycerol kinase alpha is an enzyme that in Humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-geneRating enzymes.
Clone: M6
Isotype: Mouse
Source: M6 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase fusion protein of a C-terminal portion (part of the Catalytic domain) of Rat DGKu.
Reactivity: human
Specificity: M6 is directed anti the C-terminal portion (part of the Catalytic domain) of Rat DGKa.
Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applications: Immunoprecipitation, Western blotting
Storage: Store at 4C, or in small aliquots at -20C.
Diacylglycerol kinase alpha is an enzyme that in Humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-geneRating enzymes.
Clone: M6
Isotype: Mouse
Source: M6 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase fusion protein of a C-terminal portion (part of the Catalytic domain) of Rat DGKu.
Reactivity: human
Specificity: M6 is directed anti the C-terminal portion (part of the Catalytic domain) of Rat DGKa.
Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applications: Immunoprecipitation, Western blotting
Storage: Store at 4C, or in small aliquots at -20C.
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