DGKD Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8126a
Background:
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified
Other Names:
Diacylglycerol kinase delta, DAG kinase delta, 130 kDa diacylglycerol kinase, Diglyceride kinase delta, DGK-delta, DGKD, KIAA0145
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8126a was selected from the N-term region of human DGKD . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DGKD (HGNC:2851)
Gene ID: 8527
Primary Accession: Q16760
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified
Other Names:
Diacylglycerol kinase delta, DAG kinase delta, 130 kDa diacylglycerol kinase, Diglyceride kinase delta, DGK-delta, DGKD, KIAA0145
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8126a was selected from the N-term region of human DGKD . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DGKD (HGNC:2851)
Gene ID: 8527
Primary Accession: Q16760
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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