DHCR24 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS70677
Background:
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Alternative Name:
DCE, SELADIN1, Nbla03646, seladin-1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: DHCR24 polyclonal antibody detects endogenous levels of DHCR24 protein.
Immunogen:
Recombinant protein of human DHCR24.
MW: ~ 60 kDa
Swis Prot.: Q15392
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Alternative Name:
DCE, SELADIN1, Nbla03646, seladin-1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: DHCR24 polyclonal antibody detects endogenous levels of DHCR24 protein.
Immunogen:
Recombinant protein of human DHCR24.
MW: ~ 60 kDa
Swis Prot.: Q15392
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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