DHCR24 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Synonyms: DCE, SELADIN1, Nbla03646, seladin-1

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human DHCR24

Gene Symbol: DHCR24

Gene ID: 1718

Swiss prot: Q15392

Calculated MW: 60 kDa

Recommended dilution:
WB 1:200-1000, IHC 1:30-150,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.