DHODH rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008],catalytic activity:(S)-dihydroorotate + O(2) = orotate + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,pathway:Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 4/6.,similarity:Belongs to the dihydroorotate dehydrogenase family.,

Synonyms: DHODH, Dihydroorotate dehydrogenase, quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase

Gene Name: DHODH

Gene ID: 1723

SwissProt ID: Q02127

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.