DHPS polyclonal (N-term), anti-human
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In stock
SKU
AC-AP17057a
Catalog Number: AC-AP17057a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36905
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36905
Applications: WB
Datasheet
Request Information
Background:
The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity.
Other Names:
Deoxyhypusine synthase, DHS, DHPS, DS
Target/Specificity:
This DHPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human DHPS.
Antigen Region:
16-43
Antigen Type: Synthetic Peptide
Gene Name: DHPS
Gene ID: 1725
Primary Accession: P49366
NCBI Accession: NP_001193903.1;NP_001921.1;NP_037538.1
Other Accession: NP_001921.1;NP_037538.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity.
Other Names:
Deoxyhypusine synthase, DHS, DHPS, DS
Target/Specificity:
This DHPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human DHPS.
Antigen Region:
16-43
Antigen Type: Synthetic Peptide
Gene Name: DHPS
Gene ID: 1725
Primary Accession: P49366
NCBI Accession: NP_001193903.1;NP_001921.1;NP_037538.1
Other Accession: NP_001921.1;NP_037538.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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