DHX16 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
DEAD box proteins| characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD)| are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly. Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division. This gene encodes a DEAD box protein| which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3| a region where many malignant| genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Epigenetics and nuclear signaling

Synonyms: DHX16

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year