DHX36 Polyclonal Antibody

Background:
This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DHX36, DDX36, G4R1, MLEL1, RHAU

Immunogen: Recombinant fusion protein of human DHX36 (NP_065916.2).

Swissprot: Q9H2U1
Gene ID: 170506

Calculated MW: 111 kDa/113 kDa/114 kDa
Observed MW: 114 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:200-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.