DIABLO polyclonal, anti-human, mouse

Background:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis.

Alternative Name:
DBLOH_HUMAN, DBOH, DBOH, diablo, Diablo homolog (Drosophila), Diablo homolog (Drosophila), Diablo homolog, Diablo homolog mitochondrial, DIABLO S, DIABLO S, Direct IAP binding protein with low pI, Direct IAP binding protein with low pI, Direct IAP-binding protein with low pI, FLJ10537, FLJ25049, mitochondrial, Mitochondrial Smac protein, Second mitochondria derived activator of caspase, Second mitochondria derived activator of caspase, Second mitochondria-derived activator of caspase, SMAC 3, Smac, Smac protein, Smac protein, SMAC3, SMAC3,

Application Dilution: WB: 1:500 - 1:2000

Specificity: DIABLO polyclonal antibody detects endogenous levels of DIABLO protein.

Immunogen:
Recombinant full length Human DIABLO.

MW: ~27 kDa

Swis Prot.: Q9NR28

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.