DIABLO Polyclonal Antibody

Background:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Cell Biology, Metabolism

Synonyms:
DIABLO, DFNA64, SMAC

Immunogen: Recombinant fusion protein of human DIABLO (NP_063940.1).

Swissprot: Q9NR28
Gene ID: 56616

Calculated MW: 21 kDa/22 kDa/27 kDa
Observed MW: 18 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.