DIAPH1 polyclonal, anti-human, mouse

Background:
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms: DFNA1, DIA1, DRF1, LFHL1, SCBMS, hDIA1

Cellular Location: Cell membrane Cell projection Cytoplasm cytoskeleton ruffle membrane

Immunogen:
Recombinant protein of human DIAPH1

Gene Symbol: DIAPH1

Gene ID: 1729

Swiss prot: O60610

Calculated MW: 141kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.