DIAPH1 Polyclonal Antibody

Background:
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Area: Cancer, Signal Transduction

Synonyms:
DIAPH1, DFNA1, DIA1, DRF1, LFHL1, SCBMS, hDIA1

Immunogen: Recombinant fusion protein of human DIAPH1 (NP_001073280.1).

Swissprot: O60610
Gene ID: 1729

Calculated MW: 138 kDa/140 kDa/141 kDa
Observed MW: 178 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.