DIAPH3 polyclonal (C-term), anti-human

DIAPH3 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP16587b
Catalog Number: AC-AP16587b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35590
Applications: WB
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Background:
DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).

Other Names:
Protein diaphanous homolog 3, Diaphanous-related formin-3, DRF3, MDia2, DIAPH3, DIAP3

Target/Specificity:
This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.

Antigen Region:
1061-1090

Antigen Type: Synthetic Peptide

Gene Name: DIAPH3
Gene ID: 81624
Primary Accession: Q9NSV4
NCBI Accession: NP_001035982.1;NP_001245295.1;NP_001245296.1;NP_001245297.1;NP_001245298.1;NP_001245299.1;NP_112194.2
Other Accession: NP_001035982.1;NP_112194.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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