DICER1 Polyclonal Antibody

Background:
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DCR, DCR1, Dicer 1 ribonuclease III, Dicer 1 ribonuclease type III, Dicer, DICER, DICER1, Double-strand-specific ribonuclease, Endoribonuclease Dicer, Helicase MOI, Helicase with RNase motif, HERNA, KIAA0928, MNG1, RMSE2

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Dicer

Swissprot: Q9UPY3,Q8R418

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:300-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.