DIMT1 polyclonal, anti-human, mouse

Background:
DIMT1 (DIM1 dimethyladenosine transferase 1), also known as DIMT1L or HUSSY-05, is a 313 amino acid protein that belongs to the rRNA adenine N(6)-methyltransferase family. Localized to the nucleolus, DIMT1 functions to dimethylate adjacent adenosines on the conserved hairpin loop of 18S rRNA in the 40S particle. The gene encoding DIMT1 maps to chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene.

Alternative Name:
Probable dimethyladenosine transferase, DIM1 dimethyladenosine transferase 1 homolog, DIM1 dimethyladenosine transferase 1-like, Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, Probable 18S rRNA dimethylase, Probable S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase, DIMT1, DIMT1L, HUSSY-05

Application Dilution: WB: 1:500 - 1:2000

Specificity: DIMT1 polyclonal antibody detects endogenous levels of DIMT1 protein.

Immunogen:
Recombinant full length Human DIMT1.

MW: ~ 35kDa

Swis Prot.: Q9UNQ2

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.