DIO1 Polyclonal Antibody

Background:
Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
BYE 1, BYE1, C20orf158, DATF 1, DATF-1, Death associated transcription factor 1, Death inducer obliterator 1, Death-associated transcription factor 1, Death-inducer obliterator 1, DIDO 1, DIDO 2, DIDO 3, DIDO1, DIDO1, DIDO2, DIDO3, DIO 1, DIO-1, DIO1, dJ885L7.8, DKFZp434P1115, FLJ11265, hDido 1, hDido1, KIAA0333, MGC16140

Immunogen: Recombinant protein of human DIDO1

Swissprot: Q9BTC0
Gene Accession: BC004237

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-5892/sc-11445