DIO1 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP6958a
Catalog Number: AC-AP6958a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21147
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21147
Applications: WB
Datasheet
Request Information
Background:
DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).
Other Names:
Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase, DIO1, ITDI1, TXDI1
Target/Specificity:
This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1.
Antigen Region:
30-57
Antigen Type: Synthetic Peptide
Gene Name: DIO1
Gene ID: 1733
Primary Accession: P49895
NCBI Accession: NP_000783.2;NP_001034804.1;NP_001034805.1;NP_998758.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).
Other Names:
Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase, DIO1, ITDI1, TXDI1
Target/Specificity:
This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1.
Antigen Region:
30-57
Antigen Type: Synthetic Peptide
Gene Name: DIO1
Gene ID: 1733
Primary Accession: P49895
NCBI Accession: NP_000783.2;NP_001034804.1;NP_001034805.1;NP_998758.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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