DISC1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: C1orf136, SCZD9

Cellular Location: Cell junction Cytoplasm centrosome cytoskeleton microtubule organizing center postsynaptic cell membrane postsynaptic density synapse

Immunogen:
Recombinant protein of human DISC1

Gene Symbol: DISC1

Gene ID: 27185

Swiss prot: Q9NRI5

Calculated MW: 94kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.