DISC1 Polyclonal Antibody

Background:
This gene encodes a protein with multiple coiled coil motifs which is located in the Nucleus, Cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Neuroscience

Synonyms:
C1orf136, DISC1, DISC1, Disrupted in schizophrenia 1, Disrupted in schizophrenia 1 protein, KIAA0457, RP4-730B13.1, SCZD9

Immunogen: Synthetic peptide of human DISC1

Swissprot: Q9NRI5
Gene Accession: NP_061132

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-47988/sc-134505