DISC1 Polyclonal Antibody

Background:
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Neuroscience

Synonyms:
DISC1, C1orf136, SCZD9

Immunogen: Recombinant fusion protein of human DISC1 (NP_001158009.1).

Swissprot: Q9NRI5
Gene ID: 27185

Calculated MW: 22 kDa/37-38 kDa/6-93 kDa
Observed MW: 105 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.